Oral Administration of Gelatin Hydrolysate Reduces Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled Trial

A. C. Beynen, H. W. Van Geene, H. V. Grim, P. Jacobs, T. Van der Vlerk, A. C. Beynen, H. W.V. Geene, H. V. Grim, P. Jacobs and T. V. der Vlerk

DOI : 10.3844/ajavsp.2010.102.106

American Journal of Animal and Veterinary Sciences

Volume 5, Issue 2

Pages 102-106

Abstract

Problem statement: There are indications that the intake of gelatin hydrolysate has a beneficial impact on the clinical signs of osteoarthritis in dogs. Data from a controlled trial were required to substantiate these indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of gelatin hydrolysate in the treatment of osteoarthritis. With the use of a questionnaire, the clinical signs were evaluated by the owners. For a period of 8 weeks, the test dogs daily received 10 g of gelatin hydrolysate; as a placebo, soya protein isolate was used. The supplements were mixed with the diet; all dogs were fed on the same dry food. There were 15 dogs per treatment group. Results: The administration of gelatin hydrolysate significantly improved activity (vitality) and significantly reduced stiffness and lameness. Conclusion: Gelatin hydrolysate is commonly used as a component of human foods and is generally considered as safe. It is suggested that a dose of about 2.5% in a dry food would be beneficial for dogs with osteoarthritis.

Cite this Article

Beynen, A.C., H.W. Van Geene, H.V. Grim and P. Jacobs et al., 2010. Oral Administration of Gelatin Hydrolysate Reduces Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled Trial. Am. J. Anim. Vet. Sci., 5: 102-106