Research Article Open Access

Placebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: III. Clinical Findings

Vetvicka Vaclav1, Richter Josef2, Svozil Vladimir2, Rajnohova Dobiasova Lucie2 and Kral Vlastimil2
  • 1 University of Louisville, USA
  • 2 , Europe
American Journal of Immunology
Volume 9 No. 3, 2013, 88-93

DOI: https://doi.org/10.3844/ajisp.2013.88.93

Submitted On: 28 June 2013 Published On: 20 August 2013

How to Cite: Vaclav, V., Josef, R., Vladimir, S., Lucie, R. D. & Vlastimil, K. (2013). Placebo-Driven Clinical Trials of Transfer Point Glucan #300 in Children with Chronic Respiratory Problems: III. Clinical Findings. American Journal of Immunology, 9(3), 88-93. https://doi.org/10.3844/ajisp.2013.88.93

Abstract

The role of glucan in stimulation of immune reactions has been studied for decades. In this report we focused on the effects of orally administered glucan in children with chronic respiratory problems. We measured the physical endurance using a 6MWT test and the levels of eNO in 50 children aged 8-12 years and evaluated the effects of 100 mg/d oral dose of glucan. We found significant improvements in physical indurance and exhaled nitric oxide in glucan-treated children. In addition, strong improvements in general conditions were found. Short-term oral application of natural immunomodulator β-glucan enhancers the overall health and regulation of energetic metabolism in children with chronic respiratory problems.

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Keywords

  • Glucan
  • Children
  • Physical Endurance
  • eNO
  • Placebo