@article {10.3844/ajavsp.2011.18.24,
article_type = {journal},
title = {The Ovario-Protective Effect of Erythropoietin against Oxidative Damage Associated with Reperfusion Following Ovarian Torsion in Rat},
author = {Manizheh, Sayyah-Melli and Maryamalsadat, Kazemi-Shishvan and Jafar, Solaimani-Rad and Mohammad-Reza, Rashidi and Leila, Roshangar and Nadereh, Rashtchizadeh and Elaheh, Ouladesahebmadarek and Morteza, Ghojazadeh and Omid, Mashrabi},
volume = {6},
number = {1},
year = {2011},
month = {Apr},
pages = {18-24},
doi = {10.3844/ajavsp.2011.18.24},
url = {https://thescipub.com/abstract/ajavsp.2011.18.24},
abstract = {Problem statement: To show the effect of recombinant Erythropoietin (rhEPO) on the
ovarian viability and histology in the twisted ischemic ovaries in rats, followed by detorsion.
Approach: An experimental study was conducted in primate clinic of the School of Medicine, Tabriz
University of Medical Sciences from Dec. 2008 to Apr. 2009. Forty, 4 month old Wistar rats are cased
in the present study divided into 4 groups. Ovarian ischemia was performed by torsion which was kept
stable by using a vascular microclip for 4 h. In group 1, the ovary were surgically removed, fixed and
analyzed histochemically. In group 2, the same procedure was repeated after 3 h reperfusion. In the
next two groups, the same was performed rhEPO was administrated 400 u kg−1 1 h after torsion of the
ovaries. Results: Thirty-two out of 40 rats were followed. There was a significant difference between
groups in the levels of Malondialdehyde (MDA), Total Antioxidants (TA), Superoxidase (SOD), Nitric
Oxide (NO) glutathione ( p},
journal = {American Journal of Animal and Veterinary Sciences},
publisher = {Science Publications}
}