TY - JOUR AU - Leclerc, Michel PY - 2013 TI - Like an Invertebrate Primitive Antibody JF - American Journal of Immunology VL - 9 IS - 3 DO - 10.3844/ajisp.2013.94.95 UR - https://thescipub.com/abstract/ajisp.2013.94.95 AB - Specific immune responses occur in an invertebrate: The sea star Asterias rubens. Sea star T and B lymphocytes are present in the axial organ and coopere with phagocytes and Complement components to produce a primitive antibody correlated to Igkappa genes and to complement genes: It could be composed of 4 kappa chains and present strong and highly significant homologies to Mouse IgKappa region V-IV S107B precursor gene.