Research Article Open Access

Association of Oral Contraceptives and Abnormal Pap Smear

Sayedmohsen Sayednozadi1, Mohammadreza Hassany1 and Mohammad Arash Ramezani2
  • 1 Department of Community Medicine and Health, Mashhad Medical School of Mashad Medical Sciences University, Mashad, Iran
  • 2 Department of Family and Community Medicine, Isfahan Medical School of Isfahan Medical University, Hezarjarib Street, Isfahan, Iran


To assess the hypothesis that combined Oral Contraceptive (OCs) increase the risk of cervical neoplasia, we conducted a multicenter Case-Control study in Mashhad, the capital of Khorasan province. Seventy-eight women with moderate to severe dysplasia at Pap smear as case group and one hundred fifty nine women with normal Pap smear were selected as the control group for evaluation. The both case and control groups were matched by age, parity and socioeconomic status. All of the women in this study were single partner as husband and no smoker. 30 percent of cases and 64.8 percent of controls were used OCs. The duration of OCs use was the same in both. The odds ratio for OCs consumption was 0.2 with 95% confidence interval 0.11-0.4 in Logistic regression analysis. In contrast to some other studies, our findings showed an association between OCs and cervical dysplasia and there was a protective effect of OCs for cervical dysplasia.

American Journal of Applied Sciences
Volume 2 No. 7, 2005, 1150-1152


Submitted On: 11 May 2005 Published On: 31 July 2005

How to Cite: Sayednozadi, S., Hassany, M. & Ramezani, M. A. (2005). Association of Oral Contraceptives and Abnormal Pap Smear. American Journal of Applied Sciences, 2(7), 1150-1152.

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  • Oral Contraceptives (OCs)
  • cervical dysplasia
  • pap smear
  • mashad
  • iran