Research Article Open Access

THE CLINICAL APPLICATIONS FOR AUTOMATIC DETECTION OF EXUDATES

K. Wisaeng1, N. Hiransakolwong1 and E. Pothiruk2
  • 1 Department of Computer Science, King Mongkut’s Institute of Technology Ladkrabang, Bangkok 10520, Thailand
  • 2 Ophthalmology Unit, Khonkaen Hospital, Khonkaen 40000, Thailand

Abstract

Nowadays, the retinal imaging technology has been widely used for segmenting and detecting the exudates in diabetic retinopathy patients. Unfortunately, the retinal images in Thailand are poor-quality images. Therefore, detecting of exudates in a large number by screening programs, are very expensive in professional time and may cause human error. In this study, the clinical applications for detection of exudates from the poor quality retinal image are presented. An application incorporating function, including retinal color normalization, contrast enhancement, noise removal, color space selection and removal of the optic disc, was also designed to standardize the workflow of retinal analysis. Afterward, detection of exudate based on optimal global thresholding and improved adaptive Otsu's algorithm was applied. Two experiments were conducted to validate the detection performance with local databases and a publicly available DIARETDB1 database. The first experiment showed the average sensitivity, specificity and accuracy of 93.8, 95.3 and 94.9%, respectively. The cross validation results of the second experiment, 60% (53) of the retinal images were used for training and 40% (36) for testing, the sensitivity, specificity and accuracy are 84.2, 85.9 and 85.2%, respectively. This result indicates the proposed clinical application provides an effective tool in the screening of exudates.

American Journal of Applied Sciences
Volume 11 No. 10, 2014, 1743-1756

DOI: https://doi.org/10.3844/ajassp.2014.1743.1756

Submitted On: 22 October 2012 Published On: 27 September 2014

How to Cite: Wisaeng, K., Hiransakolwong, N. & Pothiruk, E. (2014). THE CLINICAL APPLICATIONS FOR AUTOMATIC DETECTION OF EXUDATES. American Journal of Applied Sciences, 11(10), 1743-1756. https://doi.org/10.3844/ajassp.2014.1743.1756

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Keywords

  • Exudates
  • Retinal Image
  • Optimal Global Thresholding
  • Improved Adaptive Otsu's Algorithm