Research Article Open Access

Effects of 50 HZ Magnetic Field on Some Factors of Immune System in the Male Guinea Pigs

H. Sedghi1, S. Zare1, H. Hayatgeibi1, S. Alivandi1 and A. G. Ebadi2
  • 1 Urmia University, Iran
  • 2 Islamic Azad University of Sari, Iran


This study investigated the bio-effects of 50 Hz MF exposure on some Immunological factors (ACTH, cortisol and glucose levels) in male Guinea pigs. The capacity of 50 Hz Electromagnetic Fields (EMF) to interfere in the weakness of endocrine system has been a relevant fact into the scientific community, since we are more susceptible for this kind of exposure, in modern days. The 60-day-old Guinea pigs, which average of weight was 350-400 g, the Guinea pigs were divided in two groups, one of them was the control group while the other one suffered interference of a variable EMF of 50 Hz, intensity 0.207μT, 4 hours a day, for a 5 consecutive he results were collected by the weight comparison before and after of the exposure period, as well as the cortisol and glucose levels. These facts are strongly linked with the immunological system. After 5 days, the animals were anaesthetized and had their blood withdrew from their hearts. The samples produced serum where ACTH (quimiluminescent method), cortisol (radioimunoassay method) and glucose (oxidative method) levels were evaluated. The results showed that 50 Hz EMF acted on rats without any significant weight change, but affecting ACTH,cortisol and glucose levels in a significant way, 33.06% (p=0.033); 27.00% (p=0.004) and 56.23% (p=0.014) respectively when were compared with the control group. For this reason, EMF is able to change the serum levels of ACTH, cortisol and glucose, possible changing the endocrinological regulations.

American Journal of Immunology
Volume 1 No. 1, 2005, 37-41


Submitted On: 6 February 2006 Published On: 31 March 2005

How to Cite: Sedghi, H., Zare, S., Hayatgeibi, H., Alivandi, S. & Ebadi, A. G. (2005). Effects of 50 HZ Magnetic Field on Some Factors of Immune System in the Male Guinea Pigs. American Journal of Immunology, 1(1), 37-41.

  • 3 Citations



  • ACTH
  • magnetic field
  • cortisol
  • glucose
  • weight
  • guinea pigs