Research Article Open Access

Immunomodulatory Activity of Argan Oil (Argania spinosa L)

Youcef Necib1, Ahlem Bahi1, Sakina Zerizer1, Cherif Abdennour2 and Mohamed Salah Boulakoud2
  • 1 Mentouri University, Algeria
  • 2 Badji Mokhtar University, Algeria


Immunomodulatory activity of Argan oil was evaluated on phagocytic activity by carbon clearance test. Adult Albinos Wistar rats randomly divided into four groups, were the first was served as a control, while animals of treatment group were given Argan oil at dose of: 2.5, 5 and 10 mL kg-1 by gavage respectively 10 days before injected the carbon ink suspension. In carbone clearance test, Argan oil exhibited significantly phagocytic index dose-dependent against control group, indicating stimulation of the reticulo-endothelial system. Present study thus reveals that argan oil holds promise as immunomodulatory agent, which act by stimulating dose dependent phagocytic function.

American Journal of Immunology
Volume 9 No. 3, 2013, 85-87


Submitted On: 13 July 2013 Published On: 20 August 2013

How to Cite: Necib, Y., Bahi, A., Zerizer, S., Abdennour, C. & Boulakoud, M. S. (2013). Immunomodulatory Activity of Argan Oil (Argania spinosa L). American Journal of Immunology, 9(3), 85-87.

  • 2 Citations



  • Immunomodulatory
  • Phagocytic Activity
  • Carbon Clearance Rate
  • Argan Oil