Research Article Open Access

Immunological Processes in Cancer: A Link Between Inflammation and Immunity

Vanessa Jacob Victorino1, Isabela Casagrande Jeremias1 and Anne Karine Martins Assunção1
  • 1 University of São Paulo, Brazil

Abstract

Cancer is a worldwide issue and one of the most relevant death causes in child and adults. There are several causes that can lead to cancer development. It is well known that inflammation is one known hallmark of cancer and it favors tumor cells growth. Several alterations in immunological and inflammatory processes are caused in response to tumor presence and both innate and adaptive immunity have effective mechanism to destroy tumor cells. Nevertheless, distinct tumor types developed mechanisms to evade anti-tumor immunological responses. Here, we revise researches regarding inflammation and immune response during cancer development, as well as cancer signaling pathways and immunotherapy that have been performed in Brazil. The better understanding of the mechanisms regarding cancer and immunological processes is of huge importance and it may support the development of new cancer targets.

American Journal of Immunology
Volume 10 No. 4, 2014, 189-201

DOI: https://doi.org/10.3844/ajisp.2014.189.201

Published On: 17 January 2015

How to Cite: Victorino, V. J., Jeremias, I. C. & Assunção, A. K. M. (2014). Immunological Processes in Cancer: A Link Between Inflammation and Immunity. American Journal of Immunology, 10(4), 189-201. https://doi.org/10.3844/ajisp.2014.189.201

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Keywords

  • Cancer
  • Inflammation
  • Immune Response
  • Cancer Signaling
  • Immunotherapy