Research Article Open Access

Exploring the Role of Immune Complexes in Essential Hypertension

Ivan Milosevic1
  • 1 Primary Care, ZZZR, Kragujevac, Serbia


Essentialhypertension is a rise of arterial blood pressure whose etiology is unknown.Immune complexes are complexes created by the binding of an antibody to theantigen. They are also called circulating immune complexes because of its precipitation in peripheral blood vessels,commonly on the places of their bifurcation and the places of higher bloodpressure (glomerules of kidney or synovia). The goal of this study is to, bystatistical estimation, connect essential hypertension and immune complexes asa cause of many appearances. With this aim, two groups of twenty-five examineeswere questionnaire about their frequency and how long they ailed acutstreptococcal tonsillitis, which may latter cause poststreptococcalglomerulonephritis as a consequence of immune complex creation. In doing so,examinees were also questionnaired about immune complex diseases (SystemicLupus Erythematosus (SLE), Polynodosa Arteritis (PA), and PoststreptococcalGlomerulonepritis (PSG)). After all, they were questionnaired, about howfrequently and how long they used penicillin as a therapy, which also may, incertain occasions, affect the creation of immune complexes. Examined groupswere formed by patients suffering from essential hypertension, and the controlgroups were formed by randomly chosen examinees. By statistical estimating datafrom the mentioned questionnaire, we concluded that the frequency of past acutestreptococcal tonsillitis in patients with essential hypertension hasstatistical significance and the frequency of past or actual immune complexdiseases (SLE, PA, PSG); and using penicillin as a therapy does not havestatistical significance.

American Journal of Immunology
Volume 17 No. 1, 2021, 47-50


Submitted On: 4 May 2022 Published On: 2 November 2022

How to Cite: Milosevic, I. (2021). Exploring the Role of Immune Complexes in Essential Hypertension. American Journal of Immunology, 17(1), 47-50.

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  • Immune Complexes
  • Essential Hypertension