TY  - JOUR
AU  - Azimzade-Sarwar, Behzad 
AU  - Yousefzade, Gholamreza 
AU  - Narooey, Shahin 
PY  - 2005
TI  - A Case-Control Study of Effect of Opium Addiction on Myocardial Infarction
JF  - American Journal of Applied Sciences
VL  - 2
IS  - 7
DO  - 10.3844/ajassp.2005.1134.1135
UR  - https://thescipub.com/abstract/ajassp.2005.1134.1135
AB  - Ischemic Heart Disease (IHD) and Myocardial Infarction (MI) are one of the most important disease which cause mortality and morbidity. Opioid peptides and exogenous opioid such as morphine are known to exert an important cardiovascular effect. To study effect of opium addiction to incidence of MI. A Case-Control study was designed in Kerman university. 150 patients with MI was admitted to CCU and 150 matched patients admitted in surgical wards evaluate from cardiovascular risk factor and opium addiction. Analysis of data suggested no difference between two groups (P>0.05). But smoking OR = 2.45, hypertension OR = 2.65, Diabetes mellitus OR = 1.82 and Hypercholesterolemia OR = 3.16 were a risk factor for MI. Effect of opium in IHD has controversial. But recent of study defined that opioid peptides have a cardioprotective effect. Many exact and longitudinal studies should design for this purpose.