@article {10.3844/ajassp.2014.1992.1994, article_type = {journal}, title = {Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B}, author = {Khalaf, Ahmad Taha and Yuehua, Yan}, volume = {11}, year = {2015}, month = {Jan}, pages = {1992-1994}, doi = {10.3844/ajassp.2014.1992.1994}, url = {https://thescipub.com/abstract/ajassp.2014.1992.1994}, abstract = {Although it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-β and TNF-α necessary for understanding the underlying mechanisms of narrow-band UVB phototherapy. NB-UVB is effective against psoriasis without any obvious side effects and can significantly decrease serum TNF-α and promote TGF-β level of psoriasis patients. Additionally, measurement of TGF-β and TNF-αin serum could be considered as biomarkers of psoriasis activity during NB-UVB therapy.}, journal = {American Journal of Applied Sciences}, publisher = {Science Publications} }