TY  - JOUR
AU  - Khalaf, Ahmad Taha 
AU  - Yuehua, Yan 
PY  - 2015
TI  - Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B
JF  - American Journal of Applied Sciences
VL  - 11
IS  - 12
DO  - 10.3844/ajassp.2014.1992.1994
UR  - https://thescipub.com/abstract/ajassp.2014.1992.1994
AB  - Although it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-β and TNF-α necessary for understanding the underlying mechanisms of narrow-band UVB phototherapy. NB-UVB is effective against psoriasis without any obvious side effects and can significantly decrease serum TNF-α and promote TGF-β level of psoriasis patients. Additionally, measurement of TGF-β and TNF-αin serum could be considered as biomarkers of psoriasis activity during NB-UVB therapy.