@article {10.3844/ajidsp.2010.13.17, article_type = {journal}, title = {Anti-Toxoplasma gondii Antibodies in Haemodialysis Patients}, author = {Solhjoo, Kavous and Jahromi, Abdolreza Sotoodeh and Parnian-Rad, Ayeh}, volume = {6}, number = {1}, year = {2010}, month = {Mar}, pages = {13-17}, doi = {10.3844/ajidsp.2010.13.17}, url = {https://thescipub.com/abstract/ajidsp.2010.13.17}, abstract = {Problem statement: In situations of immunodeficiency, Toxoplasma gondii emerges as a life-threatening infection. Toxoplasma gondii is transmitted parenterally, flourish in immunocompromised subjects and, most toxoplasma infections are asymptomatic. Studies have shown that there is a immunodeficiency in renal failure patient such as hemodialysis patients and these patients have a high risk for many infections. There is no evidence about toxoplasmosis in hemodialysis patients in Iran. Approach: In the present study, we aimed to investigate the prevalence of anti-T. gondii antibodies in hemodialysis patients with chronic renal failure. This case-control study was carried out on 44 hemodialysis patients and 44 healthy controls for the prevalence of anti-T. gondii antibodies by ELISA. Anti-IgG, IgM and IgA T. gondii antibodies positivity were found to be 26 (59.10%), 3 (6.80%) and 3 (6.80%) of the 44 hemodialysis patients, respectively and 16 (36.40%) of the 44 control subjects were Anti-IgG T. gondii antibodies positivity and all of control subjects were negative for Anti-IgM and IgA T. gondii antibodies. The difference between them was statistically significant (p = 0.032). In addition, an increase of the seropositivity rate was detected with increasing length of time on hemodialysis treatment, indicating a statistically significant difference between these 2 parameters (p}, journal = {American Journal of Infectious Diseases}, publisher = {Science Publications} }