TY  - JOUR
AU  - Jahromi, Abdolreza Sotoodeh 
AU  - Kazemi, Akbar 
AU  - Manshoori, Gita 
AU  - Madani, Abdolhossien 
AU  - Moosavy, Seyed-Hamid 
AU  - Seddigh, Bita 
PY  - 2011
TI  - Seroprevalence of Rubella Virus in Women with Spontaneous Abortion
JF  - American Journal of Infectious Diseases
VL  - 7
IS  - 1
DO  - 10.3844/ajidsp.2011.16.19
UR  - https://thescipub.com/abstract/ajidsp.2011.16.19
AB  - Problem statement: Recurrent abortion is a difficult medical problem happening in about
1-2% of fertile women. Rubella is of high public health importance owing to teratogenic effects that
can lead to fetal death, miscarriage, stillbirth, or infants during the first 16 weeks of gestation. As there
were not data about role this virus in abortion in this area of IRAN, this study was conducted to assess
the seroprevalence of Rubella virus in women with spontaneous abortion in comparison with healthy
women (without history of abortion) in South of IRAN in order to establish basic knowledge for future
pregnancy care in this area of IRAN. Approach: Present survey basically was carried out in Shariatee
Hospital of Hormozgan University of medical sciences, Bandarabbas, Hormozgan province, located in
border of Persian Gulf-2005. A number of 220 women with definite diagnosis of previous abortion and
200 matched women with normal full term delivery and without history of miscarriage as controls
were studied as case and control groups. All obtained sera from the case and the control groups were
then tested using ELISA method for determine of rubella virus antibodies. Data was analyzed, using
SPSS software (chi square and t-test). Results: There were significant differences in seroprevalence of
anti-rubella IgG and IgM in the case group than in the control group. Conclusion: According to the
results of our research, rubella virus is presented as an etiologic factor for spontaneous abortion in this
area of IRAN.