@article {10.3844/ajidsp.2019.24.28, article_type = {journal}, title = {Cryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature Review}, author = {Al-Banyan, Maram and Alqahtani, Abdulhadi and Sheikh, Farrukh and Khaliq, Agha M. Rehan and Al Rayes, Hasan and Al-Tarifi, Ashraf and Al-Saud, Bandar and Arnaout, Rand K.}, volume = {15}, number = {1}, year = {2019}, month = {Feb}, pages = {24-28}, doi = {10.3844/ajidsp.2019.24.28}, url = {https://thescipub.com/abstract/ajidsp.2019.24.28}, abstract = {Hyper-IgM syndrome (HIGM) due to CD40 deficiency is a very rare form of combined immunodeficiency with increased susceptibility to opportunistic infections. Cryptococcus is an opportunistic infection usually affecting immunocompromised individuals. This is the first report to describe a patient with HIGM due to CD40 deficiency presenting with meningoencephalitis secondary to Cryptococcus infection.}, journal = {American Journal of Infectious Diseases}, publisher = {Science Publications} }