TY  - JOUR
AU  - Al-Banyan, Maram 
AU  - Alqahtani, Abdulhadi 
AU  - Sheikh, Farrukh 
AU  - Khaliq, Agha M. Rehan 
AU  - Al Rayes, Hasan 
AU  - Al-Tarifi, Ashraf 
AU  - Al-Saud, Bandar 
AU  - Arnaout, Rand K. 
PY  - 2019
TI  - Cryptococcal Meningoencephalitis in a Patient with Hyper IgM Syndrome Due to CD40 Deficiency: Case Report and Literature Review
JF  - American Journal of Infectious Diseases
VL  - 15
IS  - 1
DO  - 10.3844/ajidsp.2019.24.28
UR  - https://thescipub.com/abstract/ajidsp.2019.24.28
AB  - Hyper-IgM syndrome (HIGM) due to CD40 deficiency is a very rare form of combined immunodeficiency with increased susceptibility to opportunistic infections. Cryptococcus is an opportunistic infection usually affecting immunocompromised individuals. This is the first report to describe a patient with HIGM due to CD40 deficiency presenting with meningoencephalitis secondary to Cryptococcus infection.