@article {10.3844/ajidsp.2020.118.119,
article_type = {journal},
title = {Is Hydroxychloroquine a Safe and Effective Choice for Covid-19 Prophylaxis},
author = {de Almeida-Leite, Rodrigo Moisés and Bonatti, Tais Rondello and Ponzoni, Carolina Rodrigues and Korndorfer, Ana Cristina da Cunha and da Silva, Solange Bifani Tavares},
volume = {16},
number = {3},
year = {2020},
month = {Jul},
pages = {118-119},
doi = {10.3844/ajidsp.2020.118.119},
url = {https://thescipub.com/abstract/ajidsp.2020.118.119},
abstract = {The authors speculate about the possibility of Hydroxychloroquine as Covid-19 Phrophylaxis in the dose of 400 mg per week. The authors compared the experience of Malaria phrophylaxis in this dose, with acceptable safety profile. Also, we compared in vitro susceptibility of SARS-Cov-2 with that of Plasmodium falciparum. This agent show significant higher potency for the first. Also, the extended Half-life (40-50 days) make it an acceptable choice for prophylaxis. We also cite Brazilian experience with Chloroquinated Salt in the 1950s, its efficacy and feasibility. Lastly, we suggest that clinical trials should be conducted test this hypothesis.},
journal = {American Journal of Infectious Diseases},
publisher = {Science Publications}
}