@article {10.3844/ajisp.2005.48.54,
article_type = {journal},
title = {Androgen Receptor in Macrophages of Male Rat is Greater Than in Female},
author = {Ahmadi, Kazem and McCruden, Alan B.},
volume = {1},
year = {2005},
month = {Mar},
pages = {48-54},
doi = {10.3844/ajisp.2005.48.54},
url = {https://thescipub.com/abstract/ajisp.2005.48.54},
abstract = {The presence and possible sex differences of androgen receptor in peritoneal macrophages was investigated using immunomagnetic beads. Macrophages were incubated with different concentrations of [3H]-5αDHT in the presence or absence of a 100 fold excess of unlabelled 5α-DHT. Labelled cells were separated from unbound steroid by immunomagnetic beads coated with anti-rat macrophage antibody. The binding identified in the rat macrophages was highly selective towards androgenic compounds. The dissociation constant (kd) value for the receptor was calculated to be 3.3X10-9M and 5X10-9M for macrophages of male and female rat respectively. The number of receptors in each cell was 792±3 and 120±1 for male and female respectively. Indicating a sex differences in androgen receptor (p},
journal = {American Journal of Immunology},
publisher = {Science Publications}
}