@article {10.3844/ajisp.2007.1.3, article_type = {journal}, title = {HIV-1-Specific CTL Recognizing a Scarce Epitope Are Not Suppressed by HIV-1 Protease Inhibitors}, author = {Yang, Otto O.}, volume = {3}, year = {2007}, month = {Jun}, pages = {1-3}, doi = {10.3844/ajisp.2007.1.3}, url = {https://thescipub.com/abstract/ajisp.2007.1.3}, abstract = {HIV-1-protease inhibitors have received growing attention as agents that can affect proteases in human proteasomes, with potentially deleterious effects for HIV-1-specific cellular immunity. Studying the antiviral activity of HIV-1-specific CTL that recognize an epitope that is presented at limiting concentrations on infected cells, we find that several HIV-1 protease inhibitors do not affect their function. These data indicate that these protease inhibitors may have minimal impact on the antiviral activity of CTL.}, journal = {American Journal of Immunology}, publisher = {Science Publications} }