TY - JOUR AU - Yang, Otto O. PY - 2007 TI - HIV-1-Specific CTL Recognizing a Scarce Epitope Are Not Suppressed by HIV-1 Protease Inhibitors JF - American Journal of Immunology VL - 3 IS - 1 DO - 10.3844/ajisp.2007.1.3 UR - https://thescipub.com/abstract/ajisp.2007.1.3 AB - HIV-1-protease inhibitors have received growing attention as agents that can affect proteases in human proteasomes, with potentially deleterious effects for HIV-1-specific cellular immunity. Studying the antiviral activity of HIV-1-specific CTL that recognize an epitope that is presented at limiting concentrations on infected cells, we find that several HIV-1 protease inhibitors do not affect their function. These data indicate that these protease inhibitors may have minimal impact on the antiviral activity of CTL.