TY  - JOUR
AU  - Miroslav, Novak 
AU  - Vaclav, Vetvicka 
PY  - 2017
TI  - From Hyperthermia to Immunomodulating Polysaccharides
JF  - American Journal of Immunology
VL  - 13
IS  - 1
DO  - 10.3844/ajisp.2017.11.18
UR  - https://thescipub.com/abstract/ajisp.2017.11.18
AB  - Natural polysaccharides remain overlooked as part of naturally occurring bioactive molecules. The current knowledge results in numerous clinical trials, from first observations of their effects on various diseases to precise chemical characterization and decades of biological evaluation. The aim of this report is to summarize historical perspective of the route from the first anecdotical observation to the current position, with emphasis on some crucial turning points.