TY  - JOUR
AU  - Josef, Richter 
AU  - Ivana, Stiborová 
AU  - Vlastimil, Král 
AU  - Vladimir, Svozil 
AU  - Vaclav, Vetvicka 
AU  - Lucie, Rajnohová Dobiášová 
PY  - 2017
TI  - Glucan Supplementation Regulates Secretory Immunity and Stress
JF  - American Journal of Immunology
VL  - 13
IS  - 1
DO  - 10.3844/ajisp.2017.81.85
UR  - https://thescipub.com/abstract/ajisp.2017.81.85
AB  - Sixty-six children were supplemented with beta glucan and dietary nucleotides, another 63 children served as negative control. We evaluated the effects of these supplements on several aspects of secretory immunity such as levels of secretory IgA (SIgA), albumin and SIgA/albumin ratio. In addition, in order to monitor effects of physical challenges and compensatory treatments on stress and reparation of immunity, we measured levels of salivary cortisol. We found significant effects of supplementation with beta glucan on secretory IgA in children with increased physical challenge. To fully explain these findings, we will need to add additional indicators of stress and salivary immunity.