TY  - JOUR
AU  - Abdulelah, H.A.A. 
AU  - Zainal-Abidin, B.A.H. 
PY  - 2007
TI  - In Vivo Anti-malarial Tests of Nigella sativa (Black Seed) Different Extracts
JF  - American Journal of Pharmacology and Toxicology
VL  - 2
IS  - 2
DO  - 10.3844/ajptsp.2007.46.50
UR  - https://thescipub.com/abstract/ajptsp.2007.46.50
AB  - Nigella sativa (black seed) seeds have been used as a traditional medicine for the treatment of a variety of sicknesses including parasitic diseases. Intraperitoneal and oral administrations of ethanol, chloroform and aqueous seed extracts (50, 100, 200 and 400 µL kg-1) of N. sativa, were screened in the 4-day suppressive assays for their anti-malarial properties against Plasmodium berghei in mice. Both intraperitoneal and oral treatments of the seeds extracts showed suppression activities in all groups of mice with the highest values were noted by the 100 and 200 µL kg-1 doses of the ethanol extract and by the 100 µL kg-1 dose of the chloroform extract which significantly (p