@article {10.3844/ajptsp.2009.1.7,
article_type = {journal},
title = {Analgesic and Antioxidant Activity of the Hydromethanolic Extract of Mikania scandens (L.) Willd. Leaves},
author = {Hasan, S.M. Raquibul and Jamila, Mariam and Majumder, Muntasir Mamun and Akter, Raushanara and Hossain, Md. Mokarram and Mazumder, Md. Ehsanul Hoque and Alam, Md. Ashraful and Jahangir, Rumana and Rana, Md. Sohel and Arif, Md. and Rahman, Shafiqur},
volume = {4},
year = {2009},
month = {Mar},
pages = {1-7},
doi = {10.3844/ajptsp.2009.1.7},
url = {https://thescipub.com/abstract/ajptsp.2009.1.7},
abstract = {Problem statement: Mikania scandens (L.) Willd., a medicinal plant, is popularly used as herbal remedy for various ailments in Bangladesh. But the scientific basis for its medicinal use especially in pain and inflammation remains unknown. Therefore, the present study was designed to evaluate analgesic and antioxidant potential of the hydromethanol extract of the leaves of the plant. Approach: The analgesic activity was determined for its central and peripheral pharmacological actions using hotplate and tail immersion method and acetic acid-induced writhing test in mice respectively. The hydromethanol extract was also investigated for its antioxidant action using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, Nitric Oxide (NO) scavenging and reducing power assays. Results: The extract, at the dose of 250 and 500 mg kg-1, produced a significant (p},
journal = {American Journal of Pharmacology and Toxicology},
publisher = {Science Publications}
}