@article {10.3844/ajptsp.2009.94.97,
article_type = {journal},
title = {Biochemical Changes in Wistar Rats on Oral Doses of Mistletoe (Loranthus micranthus) },
author = {Edem, D. O. and Usoh, I. F.},
volume = {4},
year = {2009},
month = {Sep},
pages = {94-97},
doi = {10.3844/ajptsp.2009.94.97},
url = {https://thescipub.com/abstract/ajptsp.2009.94.97},
abstract = {Problem statement: To evaluate the effects of the water extract of the leaves of mistletoe (Loranthus micranthus) (traditionally used antidiabetic and antihypertensive) in male albino Wistar rats. Approach: The animals were divided into 4 groups (n = 6). Water extract of L. micranthus leaves was administered in graded doses of 0, 275, 551 and 827 mg kg-1 body weight (wt) of experimental animals for 21days. Blood samples were collected by cardiac puncture. The serum harvested was analyzed for some biochemical parameters, using assay kits. Results: There were no significant changes (p>0.05) in the levels of cholesterol, bilirubin, glucose, protein, urea, alkaline phosphatase and Aspartate Transaminase (AST). Alanine Transaminase (ALT) activities of the groups rats given 551 and 827 mg kg-1 body weight extracts (15.96 and 14.24 U L-1 respectively) showed significant decreases (p},
journal = {American Journal of Pharmacology and Toxicology},
publisher = {Science Publications}
}