TY  - JOUR
AU  - Yunaini, Luluk 
AU  - Sari, Puji 
AU  - Septiara, Dwi Pratami 
AU  - Junaidi, Helsy 
AU  - Antarianto, Radiana D 
PY  - 2019
TI  - Human Adipose Stem Cells in Collagen on Angiogenesis Process of Burn Healing in Rat Model: Its Number of Blood Vessels
JF  - OnLine Journal of Biological Sciences
VL  - 19
IS  - 1
DO  - 10.3844/ojbsci.2019.9.14
UR  - https://thescipub.com/abstract/ojbsci.2019.9.14
AB  - Angiogenesis in the burn wound healing process is important. The application stem cell therapy in burn wound problem is expected to increase formation of new blood vessel so that the distribution of oxygen and nutrients working well. The purpose of this study was to known effect of human Adipose Derived Stem Cell (hADSC) in collagen gel on the average number of blood vessels based on time dependent. This study used 25 male rats Sprague Dawley who had received three internal wounds with different treatments. The treatments used hADSC in collagen gel, collagen gel only and without treatment. The rats were divided into 5 groups based on the duration of observation day 0, 7, 14, 21 and 28. Rat without burn wound were used as control. Observation blood vessels number using hematoxylin-eosin staining and calculated of average number blood vessels from five filed in five mice. Statistical analysis used ANOVA one way with significance value p