Research Article Open Access

A Case-Control Study of Effect of Opium Addiction on Myocardial Infarction

Behzad Azimzade-Sarwar1, Gholamreza Yousefzade2 and Shahin Narooey2
  • 1 Department of Cardiology, CCU Ward, Shafa Hospital, Shafa Street, Kerman, Iran
  • 2 Department of Radiology, Afzalipoor Medical Center, Kerman Medical Sciences University, Iran


Ischemic Heart Disease (IHD) and Myocardial Infarction (MI) are one of the most important disease which cause mortality and morbidity. Opioid peptides and exogenous opioid such as morphine are known to exert an important cardiovascular effect. To study effect of opium addiction to incidence of MI. A Case-Control study was designed in Kerman university. 150 patients with MI was admitted to CCU and 150 matched patients admitted in surgical wards evaluate from cardiovascular risk factor and opium addiction. Analysis of data suggested no difference between two groups (P>0.05). But smoking OR = 2.45, hypertension OR = 2.65, Diabetes mellitus OR = 1.82 and Hypercholesterolemia OR = 3.16 were a risk factor for MI. Effect of opium in IHD has controversial. But recent of study defined that opioid peptides have a cardioprotective effect. Many exact and longitudinal studies should design for this purpose.

American Journal of Applied Sciences
Volume 2 No. 7, 2005, 1134-1135


Submitted On: 11 May 2005 Published On: 31 July 2005

How to Cite: Azimzade-Sarwar, B., Yousefzade, G. & Narooey, S. (2005). A Case-Control Study of Effect of Opium Addiction on Myocardial Infarction. American Journal of Applied Sciences, 2(7), 1134-1135.

  • 18 Citations



  • Opioid
  • opium addiction
  • myocardial infarction
  • risk factor