Research Article Open Access

Granulomatous Amoebic Encephalitis: Clinical Diagnosis and Management

Naveed Ahmed Khan1
  • 1 University of London London, United Kingdom


Granulomatous amoebic encephalitis (GAE) is a serious human disease with fatal consequences. With the mortality rate of more than 90%, it is not surprising that the majority of GAE infections are identified at the post-mortem stage. The most distressing aspect is that the high level of mortality is attributed to lack of awareness. Early diagnosis with aggressive treatment can lead to successful prognosis for the patient. Here, we describe a brief overview of the current understanding of the pathophysiology of GAE, available diagnostic methods, possible therapeutic interventions and the causative agents.

American Journal of Infectious Diseases
Volume 1 No. 2, 2005, 79-83


Submitted On: 20 February 2005 Published On: 30 June 2005

How to Cite: Khan, N. A. (2005). Granulomatous Amoebic Encephalitis: Clinical Diagnosis and Management. American Journal of Infectious Diseases, 1(2), 79-83.

  • 14 Citations



  • Granulomatous amoebic encephalitis (GAE)
  • clinical diagnosis
  • preventative measures
  • Acanthamoeba
  • Balamuthia mandrillaris