Case Report Open Access

Disseminated Fusarium Infections in Patients Receiving Posaconazole Prophylaxis: A Report of 2 Patients and Brief Review of the Literature

John Byrne Fournier1, Vinod Thomas1, Catherine Breen1, Jonathan Cannella1, Douglas Heiner1, Todd Roberts1 and Gail Skowron1
  • 1 M.D.Roger Williams Medical Center/Boston University School of Medicine, United States

Abstract

Fusarium is a filamentous fungi that has emerged as a frequent cause of invasive infections in immunocompromised patients. Dermatologists often play a critical role in diagnosing fusariosis, as greater than 70% of patients with disseminated infections have cutaneous involvement, and microbiologic evaluation of skin specimens provides the diagnosis in the majority of cases. Second-generation triazoles are typically the most effective medications in treating invasive Fusarium infections, and we discuss the benefits of using these medications, as well as detail the side effects of these therapeutic agents.

American Journal of Infectious Diseases
Volume 11 No. 4, 2015, 113-116

DOI: https://doi.org/10.3844/ajidsp.2015.113.116

Submitted On: 5 April 2015 Published On: 28 November 2015

How to Cite: Fournier, J. B., Thomas, V., Breen, C., Cannella, J., Heiner, D., Roberts, T. & Skowron, G. (2015). Disseminated Fusarium Infections in Patients Receiving Posaconazole Prophylaxis: A Report of 2 Patients and Brief Review of the Literature. American Journal of Infectious Diseases, 11(4), 113-116. https://doi.org/10.3844/ajidsp.2015.113.116

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Keywords

  • Fusarium
  • Invasive Fungal Infection
  • Posaconazole
  • Voriconazole