Case Report Open Access

Leprosy in a Patient Coinfected with HIV and Syphilis

Carla Andréa Avelar Pires1, Julius Caesar Mendes Soares2, Maria Amélia Lopes dos Santos3, Herbert Paulino Cordeiro4, Victoria Juliana Campos Lodi5, Raphael Pereira do Couto Rocha5, Alianne Violet Alves Chichester6 and Francisca Regina Oliveira Carneiro6
  • 1 Universidade do Estado do Pará, Brazil
  • 2 Universidade Federal do Pará, Brazil
  • 3 Universidade do Estado do Pará Brazil, Brazil
  • 4 Faculdade Metropolitana da Amazônia, Brazil
  • 5 Centro Universitário do Estado do Pará, Brazil
  • 6 Universidade do Estado do Pará, Brazil


Case report of a male patient, fifty years old, born in the Amazon region of Belém, Pará, northern Brazil. He was attended at a University service of reference in Dermatology on 09/14/2018, referring to "ball injuries" about a year ago with a sudden and progressive appearance in the abdomen with dissemination to the whole body. Three months ago he was diagnosed as a person living with the HIV Virus (PLHIV) and Antiretroviral Therapy (ART) with TDF + 3TC + DTG was started and VDRL positive (1/256) already under treatment with Benzathine penicillin. Physical examination revealed the presence of erythematous-infiltrated nodules, some of which were confluent and normochromic and were disseminated in the auricle, face, trunk, upper limbs and in a smaller number in the lower limbs. The patient was confused in the thermal sensitivity test and complained of numbness. Under suspicion of leprosy, smear microscopy of skin with 5+ positive result and histopathological biopsy of the skin lesion.  Patient was also diagnosed with Secondary Syphilis and Leprosy clinical form Virchowiana, treatment with multibacillary specific multidrug-resistant chemotherapy (MDT-MB) allied to prednisone at the inicial dose 60mg. This case shows a coinfection, Human Immunodeficiency Virus (HIV), Leprosy and Syphilis, the relation of HIV-Leprosy and the influence of Syphilis on this coinfection, changing the clinical form and their evolutions.

American Journal of Infectious Diseases
Volume 15 No. 2, 2019, 72-77


Submitted On: 4 March 2019 Published On: 29 July 2019

How to Cite: Avelar Pires, C. A., Soares, J. C. M., Lopes dos Santos, M. A., Cordeiro, H. P., Campos Lodi, V. J., Couto Rocha, R. P. D., Alves Chichester, A. V. & Oliveira Carneiro, F. R. (2019). Leprosy in a Patient Coinfected with HIV and Syphilis. American Journal of Infectious Diseases, 15(2), 72-77.

  • 2 Citations



  • Leprosy
  • HIV
  • Syphilis
  • Coinfection