Case Report Open Access

Portal Vein Thrombosis: A Saga of two Nebulous Etiologies

Ashwin Parchani1, Manjunath Totaganti1, Prasan Kumar Panda1 and Sunil Kumar KS2
  • 1 All India Institute of Medical Sciences (AIIMS), India
  • 2 All India Institute of Medical Sciences (AIIMS) Rishikesh, India

Abstract

Portal Vein Thrombosis (PVT) is the most prevalent cause of extrahepatic portal vein obstruction. Cirrhosis, inherited procoagulant conditions (such as Factor V Leiden, Antithrombin III deficiency, etc.), myeloproliferative neoplasms, hepatocellular carcinoma and operative manipulation of the portal vein are all common causes of portal vein thrombosis. Even though a diagnosis is usually made, more than 25% of patients have no clear explanation for their PVT. The authors describe two cases of portal vein thrombosis in an atypical setting-one in a middle-aged female with type 2 diabetes mellitus with pyoperitoneum and the other is in a young male coinfected with human immunodeficiency virus and hepatitis E virus. Both cases had very different outcomes and thus emphasized the notion that PVT is a potentially fatal condition demanding a thorough diagnostic workup and evaluation.

American Journal of Infectious Diseases
Volume 18 No. 1, 2022, 21-25

DOI: https://doi.org/10.3844/ajidsp.2022.21.25

Submitted On: 7 October 2021 Published On: 26 March 2022

How to Cite: Parchani, A., Totaganti, M., Panda, P. K. & KS, S. K. (2022). Portal Vein Thrombosis: A Saga of two Nebulous Etiologies. American Journal of Infectious Diseases, 18(1), 21-25. https://doi.org/10.3844/ajidsp.2022.21.25

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Keywords

  • Human Immunodeficiency Virus
  • Hepatitis E
  • Peritonitis
  • Venous Thromboembolism