Research Article Open Access

Circulation of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis Strains in Mexico

Carlos A. Vazquez-Chacon1, Armando Martinez-Guarneros1, Susana Balandrano Campos1, Julieta Luna Herrera2, Claudia Bäcker1, Livia Maria Gonçalves Rossi3, Karina Ruiz-Tovar1, Salvador Fonseca-Coronado4, Juan C. Carpio-Pedroza1, Gilberto Vaughan1 and Alejandro Escobar-Gutierrez1
  • 1 Instituto de Diagnóstico y Referencia Epidemiológicos, Mexico
  • 2 Instituto Politécnico Nacional, Mexico
  • 3 São Paulo State University, Brazil
  • 4 Universidad Nacional Autónoma de México, Mexico

Abstract

Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB isolates collected in Mexico between 2006 and 2008 were analyzed. Among 137 TB isolates, (58%) were classified as MDR exclusively, (33%) were Pre-XDR and (9%) were assigned as XDR. The results confirmed the circulation of Pre-XDR and XDR-TB in Mexico. Surveillance and drug-susceptibility testing should be improved in Mexico to monitor the circulation of XDR strains.

American Journal of Infectious Diseases
Volume 10 No. 4, 2014, 174-178

DOI: https://doi.org/10.3844/ajidsp.2014.174.178

Submitted On: 24 October 2014 Published On: 7 January 2015

How to Cite: Vazquez-Chacon, C. A., Martinez-Guarneros, A., Campos, S. B., Herrera, J. L., Bäcker, C., Gonçalves Rossi, L. M., Ruiz-Tovar, K., Fonseca-Coronado, S., Carpio-Pedroza, J. C., Vaughan, G. & Escobar-Gutierrez, A. (2014). Circulation of Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis Strains in Mexico. American Journal of Infectious Diseases, 10(4), 174-178. https://doi.org/10.3844/ajidsp.2014.174.178

  • 3,545 Views
  • 2,078 Downloads
  • 6 Citations

Download

Keywords

  • Tuberculosis
  • MDR
  • Pre-XDR
  • XDR
  • Mexico