Review Article Open Access

Theory and Strategies of Atherosclerotic Renal Artery Stenosis Treatment

Anastasia V. Poznyak1, Nikolay A. Orekhov1, Gulalek Amanmyradovna Babayeva2, Maria Andreevna Vergun2, Ksenia Olegovna Lapshina3, Vasily N. Sukhorukov4 and Alexander N. Orekhov1
  • 1 Institute for Atherosclerosis Research, Moscow, Russia, Russia
  • 2 Institute of Experimental Cardiology, National Medical Research Center of Cardiology, Moscow, Russia, Russia
  • 3 Faculty of Biology and Biotechnology, National Research University Higher School of Economics, Moscow, Russia, Russia
  • 4 Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, Moscow, Russia, Russia

Abstract

Atherosclerosis is a disease that affects large arteries and contributes to the development of cardiovascular disease and adverse events. The main characteristic of this disease is the formation of plaques that narrow the lumen of the vessel. However, atherosclerosis is not the only cause of vasoconstriction. For example, various causes may be involved in renal artery stenosis, such as vasculitis and fibromuscular dysplasia. Nonetheless, atherosclerosis remains one of the major problems associated with it. By itself, renal artery stenosis leads to issues with blood supply to the kidneys and can be one of the causes of kidney failure. In our review, we examined in detail the pathology of atherosclerotic renal artery stenosis, focusing on diagnostic methods and treatment strategies.

American Journal of Biochemistry and Biotechnology
Volume 21 No. 3, 2025, 307-318

DOI: https://doi.org/10.3844/ajbbsp.2025.307.318

Submitted On: 23 June 2024 Published On: 4 January 2026

How to Cite: Poznyak, A. V., Orekhov, N. A., Babayeva, G. A., Vergun, M. A., Lapshina, K. O., Sukhorukov, V. N. & Orekhov, A. N. (2025). Theory and Strategies of Atherosclerotic Renal Artery Stenosis Treatment. American Journal of Biochemistry and Biotechnology, 21(3), 307-318. https://doi.org/10.3844/ajbbsp.2025.307.318

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Keywords

  • Atherosclerosis
  • ARAS
  • Therapeutic Strategies