American Journal of Biochemistry and Biotechnology

Functional and Structural Proteomics

Introduction to Structural and Functional Proteomics

One major problem still escaping a solution to humans is cancer that is being studied with some result at molecular scale as strongly interlinked to differentiation, ageing and proliferation, but also to ecology. Its solution requires more coordinated efforts worldwide at the basic level subtracting the lead to the corporations that have been so far quite ineffective in both side of the Ocean linked to hospital and health-related institutions and we will be able to solve it only approaching with quite more focus the molecular quantitative scale correlating for human race benefits all pending problems in medicine (ageing, differentiation, cancer metastasis) at the protein level. As Guest Editor I am here by providing in this Special Issue of American Journal of Biochemistry and Biotechnology six representative examples of these efforts from both the western and eastern parts of the world, namely six examples going:

1. from molecular dynamics simulations of M2 protein in potential drugs discovery to an application to influenza virus
2. from NAPPA QCM_D Nanoconductometric Assay to Drug-Protein Interactions for Clinical Research,
3. from Raman Spectrocopy to Protein Crystal Nucleation and Growth
4. from structural characterization at the atomic level of a molecular nano-machine to the state of the art of Helicobacter pylori flagellum organization
5. from Synchrotron Powder Diffraction Study to the Radiation Damage with Langmuir Blodgett Nanotemplate Crystallised Protein
6. from Site-directed Mutagenesis to probing the Substrate Specificity and Intersubunit Interactions of Brevundimonas diminuta Glutaryl Acylase

Volume 10, Issue 3 (2014)